Targeting SMAD-Dependent Signaling: Considerations in Epithelial and Mesenchymal Solid Tumors
SMADs are the canonical intracellular effector proteins of the TGF-β (transforming growth factor-β). SMADs translocate from plasma membrane receptors to the nucleus regulated by many SMAD-interacting proteins through phosphorylation and other post-translational modifications that govern their nucleo...
Saved in:
Main Authors: | Farhana Runa (Author), Gabriela Ortiz-Soto (Author), Natan Roberto de Barros (Author), Jonathan A. Kelber (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2024-03-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
CD82 attenuates TGF-β1-mediated epithelial-mesenchymal transition by blocking smad-dependent signaling in ARPE-19 cells
by: Hyesook Lee, et al.
Published: (2022) -
<i>Cinnamomum bejolghota</i> Extract Inhibits Colorectal Cancer Cell Metastasis and TGF-β1-Induced Epithelial-Mesenchymal Transition via Smad and Non-Smad Signaling Pathway
by: Athicha Kittiwattanokhun, et al.
Published: (2022) -
Dulaglutide Ameliorates Intrauterine Adhesion by Suppressing Inflammation and Epithelial-Mesenchymal Transition via Inhibiting the TGF-β/Smad2 Signaling Pathway
by: Yifan Wang, et al.
Published: (2023) -
Hesperidin inhibits the epithelial to mesenchymal transition induced by transforming growth factor-β1 in A549 cells through Smad signaling in the cytoplasm
by: Zhouxin Ren, et al.
Published: (2019) -
Smad signalling in the ovary
by: Mottershead David G, et al.
Published: (2006)