Identification and in vitro validation of neoantigens for immune activation against high-risk pediatric leukemia cells

• Váldodahkkit: Satbir Thakur (Dahkki), Mohit Jain (Dahkki), Chunfen Zhang (Dahkki), Candice Major (Dahkki), Kevin J. Bielamowicz (Dahkki), Norman J. Lacayo (Dahkki), Olena Vaske (Dahkki), Victor Lewis (Dahkki), Luis Murguia-Favela (Dahkki), Aru Narendran (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Taylor & Francis Group, 2021-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

There is experimental and clinical data to indicate the contribution of immune-escape mechanisms in relapsed/refractory pediatric leukemia. Studies have shown the accumulation of mutations that translate to peptides containing tumor-specific epitopes (neoantigens). The effectiveness of neoantigen-ba...