Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner.

• Autori principali: Jan-Hendrik Schroeder (Autore), David McCarthy (Autore), Tadge Szestak (Autore), Darren A Cook (Autore), Mark J Taylor (Autore), Alister G Craig (Autore), Charlotte Lawson (Autore), Rachel A Lawrence (Autore)
• Natura: Libro
• Pubblicazione: Public Library of Science (PLoS), 2017-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Brugia malayi causes the human tropical disease, lymphatic filariasis. Microfilariae (Mf) of this nematode live in the bloodstream and are ingested by a feeding mosquito vector. Interestingly, in a remarkable co-evolutionary adaptation, Mf appearance in the peripheral blood follows a circadian perio...