Cover Image

Development and validation of an HPLC method for the simultaneous determination of artesunate and mefloquine hydrochloride in fixed-dose combination tablets

The present study developed and validated an HPLC method for the simultaneous determination of artesunate (AS) and mefloquine hydrochloride (MQ) in fixed-dose combination tablets, according to ICH guidelines. The chromatographic separation was carried out on an XBridge C18 (250 x 4.6 mm i.d., 5 µm p...

Full description

Saved in:

Bibliographic Details
Main Authors:	Fernando Henrique Andrade Nogueira (Author), Naialy Fernandes Araújo Reis (Author), Paula Rocha Chellini (Author), Isabela da Costa César (Author), Gerson Antônio Pianetti (Author)
Format:	Book
Published:	Universidade de São Paulo, 2013-12-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Development and validation of novel method for simultaneous estimation of Atovaquone and Mefloquine hydrochloride in bulk drug using RP-HPLC
by: Sanyam Sharma, et al.
Published: (2020)

Development and validation of a stability indicating HPLC method to determine diltiazem hydrochloride in tablets and compounded capsules
by: Mateus Araújo Castro e Souza, et al.
Published: (2017)

Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium: a randomized, exploratory, open-label trial.
by: Jennifer Keiser, et al.
Published: (2014)

Analytical method development and validation for simultaneous estimation of mefloquine hydrochloride and artemether in bulk drug by simultaneous equation method
by: Amit Choudhary, et al.
Published: (2020)

Development and validation of stability-indicating RP-HPLC method for the simultaneous determination of ertugliflozin pidolate and metformin hydrochloride in bulk and tablets
by: K. Sravana Kumari, et al.
Published: (2020)

Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria
by: Walter RJ Taylor, et al.

Development of the RP-HPLC Method for Simultaneous Determination and Quantification of Artemether and Lumefantrine in Fixed-Dose Combination Pharmaceutical Dosage Forms
by: Simon Nyarko, et al.
Published: (2024)

RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF FINASTERIDE AND TAMSULOSIN IN TABLET FORMULATIONS
by: Ashu Mittal, et al.
Published: (2015)

Comparative application of derivative spectrophotometric and HPLC techniques for the simultaneous determination of lamivudine and tenofovir disoproxil fumarate in fixed-dose combined drugs
by: Edebi N. Vaikosen, et al.
Published: (2023)

Simultaneous estimation of nebivolol hydrochloride and amlodipine besylate in human plasma employing an innovative HPLC chromatographic method
by: Kaveri T. Vaditake, et al.
Published: (2024)

Development and validation of an rp-hplc method for simultaneous determination of Ramipril and Amlodipine in tablets
by: Shi-Ying Dai, et al.
Published: (2013)

Development and validation of a normal-phase HPTLC method for the simultaneous analysis of Lamivudine and Zidovudine in fixed-dose combination tablets
by: Palani Venkatesh, et al.
Published: (2012)

Mefloquine-curcumin combinations improve host mitochondrial respiration and decrease mitotoxic effects of mefloquine in Plasmodium berghei-infected mice
by: John Oludele Olanlokun, et al.
Published: (2024)

Stability-Indicating HPLC Method for Simultaneous Determination of Chloramphenicol, Dexamethasone Sodium Phosphate and Tetrahydrozoline Hydrochloride in Ophthalmic Solution
by: Hashem AlAani, et al.
Published: (2016)

Evaluation of stability and simultaneous determination of fimasartan and amlodipine by a HPLC method in combination tablets
by: Hyeon Woo Moon, et al.
Published: (2014)

Simultaneous Determination of Paracetamol ,Chlorpheniramine Maleate and Ascorbic Acid in Tablet Dosage Form by HPLC
by: kahtan J. Hasson, et al.
Published: (2012)

Mefloquine--an aminoalcohol with promising antischistosomal properties in mice.
by: Jennifer Keiser, et al.
Published: (2009)

Rationale for use mefloquine for COVID-19 treatment
by: V. A. Otdelenov, et al.
Published: (2020)

Development and validation of a HILIC-HPLC-ELSD method for simultaneous determination of glucosamine hydrochloride and chondroitin sulfate in dietary supplements
by: Etik Wahyuningsih, et al.
Published: (2023)

A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated <it>Plasmodium falciparum </it>malaria in eastern Sudan
by: Osman Maha E, et al.
Published: (2006)

Malaria-Infected Mice Are Cured by a Single Low Dose of a New Silylamide Trioxane Plus Mefloquine
by: Theresa A. Shapiro, et al.
Published: (2009)

Simultaneous determination of clobutinol hydrochloride and doxylamine succinate from syrups by RP HPLC using a new stationary phase containing embedded urea polar groups
by: Paulo Cesar Pires Rosa, et al.
Published: (2012)

A new stability-indicating RP-HPLC method for the determination of dicyclomine hydrochloride and dimethicone combination in tablet dosage forms
by: J. Saroja, et al.
Published: (2021)

Stability-indicating HPLC method for determination of amiodarone hydrochloride and its impurities in tablets: a detailed forced degradation study
by: Ana Silva Coelho, et al.
Published: (2020)

Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Metformin Hydrochloride in Tablet Dosage Forms by HPLC
by: Mousa Sha'at, et al.
Published: (2022)

Rapid Study on Mefloquine Hydrochloride Complexation with Hydroxypropyl-β-Cyclodextrin and Randomly Methylated β-Cyclodextrin: Phase Diagrams, Nuclear Magnetic Resonance Analysis, and Stability Assessment
by: Amaury Durand, et al.
Published: (2023)

The rationale for recommending fixed-dose combination tablets for treatment of tuberculosis
by: Blomberg Bjørn, et al.
Published: (2001)

An effective stability indicating RP-HPLC method for simultaneous estimation of Dolutegravir and Lamivudine in bulk and their tablet dosage form
by: Ramreddy Godela, et al.
Published: (2020)

Validated gradient stability indicating HPLC method for determining Diltiazem Hydrochloride and related substances in bulk drug and novel tablet formulation
by: Vivekanand A. Chatpalliwar, et al.
Published: (2012)

Novel HPLC-UV method for simultaneous determination of valsartan and atenolol in fixed dosage form; Study of green profile assessment
by: Kateryna Peleshok, et al.
Published: (2021)

Development and validation of stability-indicating RP-HPLC method for the simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from nasal spray dosage form
by: Bhaskar Musmade, et al.
Published: (2021)

Pharmacokinetics of fixed-dose combination of atorvastatin and metformin compared with individual tablets
by: Ghim JL, et al.
Published: (2019)

A stability indicating UPLC method development and validation for the simultaneous estimation of nateglinide and metformin hydrochloride in bulk and tablet dosage form
by: Ashritha Narikimalli, et al.
Published: (2023)

Controlled release tablets of verapamil hydrochloride
by: Treephu Kimlek, et al.
Published: (2016)

The use of capillary electrophoresis in the simultaneous determination of fixed-dose combination drugs for cardiovascular diseases
by: Gabriel Hancu, et al.
Published: (2020)

Application of quality by design approach in RP-HPLC method development for simultaneous estimation of saxagliptin and dapagliflozin in tablet dosage form
by: Aruna Gundala, et al.
Published: (2019)

Enhancing dissolution of artesunate from immediate release tablets using a green granulation technique
by: Akram ahmad Bashir, et al.
Published: (2019)

Comparison of microbiological assay and HPLC-UV for determination of fluconazole in capsules
by: Kelly Marques Queiroz, et al.
Published: (2009)

Novel RP-HPLC method for simultaneous determination of dapagliflozin and teneligliptin in tablet formulation and identification of degradation products by LC-MS/MS
by: Thummar Kashyap, et al.
Published: (2024)

Analytical method development and validation for simultaneous estimation of monoammonium glycyrrhizinate and sennoside-B in polyherbal laxative tablet using RP-HPLC
by: Madhavi Patel, et al.
Published: (2021)