Oleanolic acid attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells

• Egile Nagusiak: Wei-ming He (Egilea), Jia-qi Yin (Egilea), Xu-dong Cheng (Egilea), Xun Lu (Egilea), Li Ni (Egilea), Yi Xi (Egilea), Gui-dong Yin (Egilea), Guo-yuan Lu (Egilea), Wei Sun (Egilea), Ming-gang Wei (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2018-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Epithelial-to-mesenchymal transition (EMT) plays an important role in the progression of renal interstitial fibrosis, which finally leads to renal failure. Oleanolic acid (OA), an activator of NF-E2-related factor 2 (Nrf2), is reported to attenuate renal fibrosis in mice with uni...