Stimulation of Histamine H1 Receptor Up-Regulates Histamine H1 Receptor Itself Through Activation of Receptor Gene Transcription

• 主要な著者: Asish K. Das (著者), Sachiho Yoshimura (著者), Ryoko Mishima (著者), Katsumi Fujimoto (著者), Hiroyuki Mizuguchi (著者), Shrabanti Dev (著者), Yousuke Wakayama (著者), Yoshiaki Kitamura (著者), Shuhei Horio (著者), Noriaki Takeda (著者), Hiroyuki Fukui (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2007-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Histamine is a major mediator in allergy acting mainly through the histamine H1 receptor (H1R). Although H1R up-regulation has been suggested as an important step for induction of allergic symptoms, little is known about the regulation of H1R level. Here we report that the activation of H1R up-regul...