Qualification and Application of a Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometric Method for the Determination of Adalimumab in Rat Plasma

• Prif Awduron: Yuri Park (Awdur), Nahye Kim (Awdur), Jangmi Choi (Awdur), Min-Ho Park (Awdur), Byeong ill Lee (Awdur), Seok-Ho Shin (Awdur), Jin-Ju Byeon (Awdur), Young G. Shin (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2018-05-01T00:00:00Z.
• Pynciau: article
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A liquid chromatography–quadrupole time-of-flight (Q-TOF) mass spectrometric method was developed for early-stage research on adalimumab in rats. The method consisted of immunoprecipitation followed by tryptic digestion for sample preparation and LC-QTOF-MS/MS analysis of specific signatur...