IGF2 deficiency promotes liver aging through mitochondrial dysfunction and upregulated CEBPB signaling in d-galactose-induced aging mice

• Asıl Yazarlar: Xiaohai Zhou (Yazar), Bowen Tan (Yazar), Weiwei Gui (Yazar), Caiping Zhou (Yazar), Hanxin Zhao (Yazar), Xihua Lin (Yazar), Hong Li (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2023-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background Liver aging, marked by cellular senescence and low-grade inflammation, heightens susceptibility to chronic liver disease and worsens its prognosis. Insulin-like growth factor 2 (IGF2) has been implicated in numerous aging-related diseases. Nevertheless, its role and underlying mo...