Caffeine reduces deficits in mechanosensation and locomotion induced by L-DOPA and protects dopaminergic neurons in a transgenic Caenorhabditis elegans model of Parkinson's disease

Context L-DOPA is the first-line drug for Parkinson's disease (PD). However, chronic use can lead to dyskinesia. Caffeine, which is a known neuroprotectant, can potentially act as an adjunct to minimise adverse effects of L-DOPA. Objectives This study determined changes in terms of neurodegener...

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Hoofdauteurs: Rafael Vincent M. Manalo (Auteur), Paul Mark B. Medina (Auteur)
Formaat: Boek
Gepubliceerd in: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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