In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies

• Auteurs principaux: Gauresh Somani (Auteur), Chinmay Kulkarni (Auteur), Prashant Shinde (Auteur), Rupesh Shelke (Auteur), Kirti Laddha (Auteur), Sadhana Sathaye (Auteur)
• Format: Livre
• Publié: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Introduction: Alzheimer's disease (AD) has increased at an alarming rate and is now a worldwide health problem. Inhibitors of acetylcholinesterase (AChE) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for AD. Psoralen was investigated as inhibitor of A...