In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies

• Main Authors: Gauresh Somani (Author), Chinmay Kulkarni (Author), Prashant Shinde (Author), Rupesh Shelke (Author), Kirti Laddha (Author), Sadhana Sathaye (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Alzheimer's disease (AD) has increased at an alarming rate and is now a worldwide health problem. Inhibitors of acetylcholinesterase (AChE) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for AD. Psoralen was investigated as inhibitor of A...