In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies

• मुख्य लेखकों: Gauresh Somani (लेखक), Chinmay Kulkarni (लेखक), Prashant Shinde (लेखक), Rupesh Shelke (लेखक), Kirti Laddha (लेखक), Sadhana Sathaye (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: Alzheimer's disease (AD) has increased at an alarming rate and is now a worldwide health problem. Inhibitors of acetylcholinesterase (AChE) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for AD. Psoralen was investigated as inhibitor of A...