In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies

• Váldodahkkit: Gauresh Somani (Dahkki), Chinmay Kulkarni (Dahkki), Prashant Shinde (Dahkki), Rupesh Shelke (Dahkki), Kirti Laddha (Dahkki), Sadhana Sathaye (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Introduction: Alzheimer's disease (AD) has increased at an alarming rate and is now a worldwide health problem. Inhibitors of acetylcholinesterase (AChE) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for AD. Psoralen was investigated as inhibitor of A...