Virtual Screening Based on Machine Learning Explores Mangrove Natural Products as KRAS^G12C Inhibitors

• Päätekijät: Lianxiang Luo (Tekijä), Tongyu Zheng (Tekijä), Qu Wang (Tekijä), Yingling Liao (Tekijä), Xiaoqi Zheng (Tekijä), Ai Zhong (Tekijä), Zunnan Huang (Tekijä), Hui Luo (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Mangrove secondary metabolites have many unique biological activities. We identified lead compounds among them that might target KRAS^G12C<b>.</b> KRAS is considered to be closely related to various cancers. A variety of novel small molecules that directly target KR...