On-demand integrated nano-engager converting cold tumors to hot via increased DNA damage and dual immune checkpoint inhibition
Cancer immunotherapy has become a promising strategy. However, the effectiveness of immunotherapy is restricted in "cold tumors" characterized with insufficient T cells intratumoral infiltration and failed T cells priming. Herein, an on-demand integrated nano-engager (JOT-Lip) was develope...
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Main Authors: | Xiaoqing Liu (Author), Shuang Liang (Author), Xiao Sang (Author), Lili Chang (Author), Shunli Fu (Author), Han Yang (Author), Huizhen Yang (Author), Yongjun Liu (Author), Na Zhang (Author) |
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Format: | Book |
Published: |
Elsevier,
2023-04-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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