Density functional theory (DFT), molecular docking, and xanthine oxidase inhibitory studies of dinaphthodiospyrol S from Diospyros kaki L

• Hauptverfasser: Tareq Abu-Izneid (VerfasserIn), Abdur Rauf (VerfasserIn), Zubair Ahmad (VerfasserIn), Abdul Wadood (VerfasserIn), Khurshid Ayub (VerfasserIn), Naveed Muhammad (VerfasserIn), Yahya S. Al-Awthan (VerfasserIn), Maria Maqbool (VerfasserIn), Omar S. Bahattab (VerfasserIn), Hassan A. Hemeg (VerfasserIn), Saima Naz (VerfasserIn), Dorota Formanowicz (VerfasserIn)
• Format: Buch
• Veröffentlicht: Elsevier, 2024-02-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

In this work, we investigated Diospyros kaki extract and an isolated compound for their potential as xanthine oxidase (XO) inhibitors, a target enzyme involved in inflammatory disorders. The prepared extract was subjected to column chromatography, and dinaphthodiospyrol S was isolated. Then XO inhib...