Density functional theory (DFT), molecular docking, and xanthine oxidase inhibitory studies of dinaphthodiospyrol S from Diospyros kaki L

• প্রধান লেখক: Tareq Abu-Izneid (লেখক), Abdur Rauf (লেখক), Zubair Ahmad (লেখক), Abdul Wadood (লেখক), Khurshid Ayub (লেখক), Naveed Muhammad (লেখক), Yahya S. Al-Awthan (লেখক), Maria Maqbool (লেখক), Omar S. Bahattab (লেখক), Hassan A. Hemeg (লেখক), Saima Naz (লেখক), Dorota Formanowicz (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2024-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

In this work, we investigated Diospyros kaki extract and an isolated compound for their potential as xanthine oxidase (XO) inhibitors, a target enzyme involved in inflammatory disorders. The prepared extract was subjected to column chromatography, and dinaphthodiospyrol S was isolated. Then XO inhib...