Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves

• Egile Nagusiak: Mari Chiyoya (Egilea), Kazuhiko Seya (Egilea), Zaiqiang Yu (Egilea), Kazuyuki Daitoku (Egilea), Shigeru Motomura (Egilea), Tadaatsu Imaizumi (Egilea), Ikuo Fukuda (Egilea), Ken-Ichi Furukawa (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2018-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Calcified aortic valve stenosis (CAS) is a common heart valve disease in elderly people, and is mostly accompanied by ectopic valve calcification. We recently demonstrated that tumor necrosis factor-α (TNF-α) induces calcification of human aortic valve interstitial cells (HAVICs) obtained from CAS p...