The Modulation of Cholesterol Metabolism Is Involved in the Antiviral Effect of Nitazoxanide

• Auteurs principaux: Claudio Fenizia (Auteur), Salomè Valentina Ibba (Auteur), Claudia Vanetti (Auteur), Sergio Strizzi (Auteur), Jean-François Rossignol (Auteur), Mara Biasin (Auteur), Daria Trabattoni (Auteur), Mario Clerici (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-07-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

We previously investigated the role of Nitazoxanide (NTZ), a thiazolide endowed with antiviral and antiparasitic activity, in HIV-1 infection. NTZ treatment in primary isolated PBMCs was able to reduce HIV-1 infection in vitro by inducing the expression of a number of type-I interferon-stimulated ge...