N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression

• Main Authors: Xun Xi (Author), Zi-Xuan Li (Author), Yi Zhao (Author), Hong Liu (Author), Shuai Chen (Author), Dong-Xu Liu (Author)
• Format: Bog
• Udgivet: Elsevier, 2022-04-01T00:00:00Z.
• Fag: article
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Background/purpose: Mechanical stress plays a vital role in osteogenic differentiation of periodontal ligament stem cells (PDLSCs). Cyclic mechanical stress may up-regulate reactive oxygen species (ROS) level. N-acetylcysteine (NAC) possesses powerful antioxidant capacity. However, it is undefined t...