GENE-IS: Time-Efficient and Accurate Analysis of Viral Integration Events in Large-Scale Gene Therapy Data

Integration site profiling and clonality analysis of viral vector distribution in gene therapy is a key factor to monitor the fate of gene-corrected cells, assess the risk of malignant transformation, and establish vector biosafety. We developed the Genome Integration Site Analysis Pipeline (GENE-IS...

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Main Authors: Saira Afzal (Author), Stefan Wilkening (Author), Christof von Kalle (Author), Manfred Schmidt (Author), Raffaele Fronza (Author)
Format: Book
Published: Elsevier, 2017-03-01T00:00:00Z.
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3rd Floor Main Library

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