Effects of molidustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, on sodium dynamics in hypertensive subtotally nephrectomized rats

• Main Authors: Anqi Zhang (Author), Daisuke Nakano (Author), Norihiko Morisawa (Author), Kento Kitada (Author), Wararat Kittikulsuth (Author), Asadur Rahman (Author), Takashi Morikawa (Author), Yoshio Konishi (Author), Akira Nishiyama (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitors were developed for treatment of renal anemia. Patients applicable for HIF-PHD inhibitor treatment experience complications such as chronic kidney disease, whereby water and electrolyte homeostasis is disrupted. The effects of hypoxia-i...