Effects of molidustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, on sodium dynamics in hypertensive subtotally nephrectomized rats

• मुख्य लेखकों: Anqi Zhang (लेखक), Daisuke Nakano (लेखक), Norihiko Morisawa (लेखक), Kento Kitada (लेखक), Wararat Kittikulsuth (लेखक), Asadur Rahman (लेखक), Takashi Morikawa (लेखक), Yoshio Konishi (लेखक), Akira Nishiyama (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2021-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitors were developed for treatment of renal anemia. Patients applicable for HIF-PHD inhibitor treatment experience complications such as chronic kidney disease, whereby water and electrolyte homeostasis is disrupted. The effects of hypoxia-i...