Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma

• প্রধান লেখক: Rosie T. Jiang (লেখক), Anna Yemelyanova (লেখক), Deyin Xing (লেখক), Ravi K. Anchoori (লেখক), Jun Hamazaki (লেখক), Shigeo Murata (লেখক), Jeffrey D. Seidman (লেখক), Tian-Li Wang (লেখক), Richard B. S. Roden (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2017-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Ovarian carcinoma is highly dependent on the ubiquitin proteasome system (UPS), but its clinical response to treatment with the proteasome inhibitor bortezomib has been disappointing. This has driven exploration of alternate approaches to target the UPS in ovarian cancer. Recentl...