Administration of Bicarbonate Protects Mitochondria, Rescues Retinal Ganglion Cells, and Ameliorates Visual Dysfunction Caused by Oxidative Stress

• 主要な著者: Tonking Bastola (著者), Guy A. Perkins (著者), Viet Anh Nguyen Huu (著者), Saeyeon Ju (著者), Keun-Young Kim (著者), Ziyao Shen (著者), Dorota Skowronska-Krawczyk (著者), Robert N. Weinreb (著者), Won-Kyu Ju (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-06-01T00:00:00Z.
• 主題: article
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Oxidative stress is a key factor causing mitochondrial dysfunction and retinal ganglion cell (RGC) death in glaucomatous neurodegeneration. The cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) signaling pathway is involved in mitochondrial protection, promoting RGC survival. Soluble aden...