Administration of Bicarbonate Protects Mitochondria, Rescues Retinal Ganglion Cells, and Ameliorates Visual Dysfunction Caused by Oxidative Stress

• Asıl Yazarlar: Tonking Bastola (Yazar), Guy A. Perkins (Yazar), Viet Anh Nguyen Huu (Yazar), Saeyeon Ju (Yazar), Keun-Young Kim (Yazar), Ziyao Shen (Yazar), Dorota Skowronska-Krawczyk (Yazar), Robert N. Weinreb (Yazar), Won-Kyu Ju (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2024-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Oxidative stress is a key factor causing mitochondrial dysfunction and retinal ganglion cell (RGC) death in glaucomatous neurodegeneration. The cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) signaling pathway is involved in mitochondrial protection, promoting RGC survival. Soluble aden...