Allelic variants of <it>IL1R1 </it>gene associate with severe hand osteoarthritis

• Main Authors: Harilainen Arsi (Author), Saarela Janna (Author), Kouhia Sanna T (Author), Näkki Annu (Author), Tallroth Kaj (Author), Videman Tapio (Author), Battié Michele C (Author), Kaprio Jaakko (Author), Peltonen Leena (Author), Kujala Urho M (Author)
• Format: Book
• Published: BMC, 2010-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>In search for genes predisposing to osteoarthritis (OA), several genome wide scans have provided evidence for linkage on 2q. In this study we targeted a 470 kb region on 2q11.2 presenting the locus with most evidence for linkage to s...