Allelic variants of <it>IL1R1 </it>gene associate with severe hand osteoarthritis

• Egile Nagusiak: Harilainen Arsi (Egilea), Saarela Janna (Egilea), Kouhia Sanna T (Egilea), Näkki Annu (Egilea), Tallroth Kaj (Egilea), Videman Tapio (Egilea), Battié Michele C (Egilea), Kaprio Jaakko (Egilea), Peltonen Leena (Egilea), Kujala Urho M (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2010-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>In search for genes predisposing to osteoarthritis (OA), several genome wide scans have provided evidence for linkage on 2q. In this study we targeted a 470 kb region on 2q11.2 presenting the locus with most evidence for linkage to s...