Development of novel liver-targeting glucocorticoid prodrugs

• Κύριοι συγγραφείς: Yazheng Wang (Συγγραφέας), Dandan Guo (Συγγραφέας), Rebecca Winkler (Συγγραφέας), Xiaohong Lei (Συγγραφέας), Xiaojing Wang (Συγγραφέας), Jennifer Messina (Συγγραφέας), Juntao Luo (Συγγραφέας), Hong Lu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2024-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Background: Glucocorticoids (GCs) are widely used in the treatment of inflammatory liver diseases and sepsis, but GC's various side effects on extrahepatic tissues limit their clinical benefits. Liver-targeting GC therapy may have multiple advantages over systemic GC therapy. The purpose of thi...