Cutaneous Effects of Notch Inhibitor Therapy: A Report of Two Cases

• Main Authors: Claire J. Wiggins (Author), Susan Y. Chon (Author)
• 格式: 圖書
• 出版: Hindawi Limited, 2020-01-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

As aberrant Notch signaling has been linked to cancerous growth, Notch inhibitors represent a novel category of targeted oncological therapy. Notch pathways in tumor cells may contribute to proliferation or limit apoptosis and differentiation. Healthy skin differentiation and homeostasis are reliant...