Cutaneous Effects of Notch Inhibitor Therapy: A Report of Two Cases

• Asıl Yazarlar: Claire J. Wiggins (Yazar), Susan Y. Chon (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2020-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

As aberrant Notch signaling has been linked to cancerous growth, Notch inhibitors represent a novel category of targeted oncological therapy. Notch pathways in tumor cells may contribute to proliferation or limit apoptosis and differentiation. Healthy skin differentiation and homeostasis are reliant...