Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
The STE20 kinase family is a complex signalling cascade that regulates cytoskeletal organisation and modulates the stress response. This signalling cascade includes various kinase mediators, such as TAOK1 and MAP4K5. The dysregulation of the STE20 kinase pathway is linked with cancer malignancy. A s...
Saved in:
Main Authors: | Min-Wu Chao (Author), Tony Eight Lin (Author), Wei-Chun HuangFu (Author), Chao-Di Chang (Author), Huang-Ju Tu (Author), Liang-Chieh Chen (Author), Shih-Chung Yen (Author), Tzu-Ying Sung (Author), Wei-Jan Huang (Author), Chia-Ron Yang (Author), Shiow-Lin Pan (Author), Kai-Cheng Hsu (Author) |
---|---|
Format: | Book |
Published: |
Taylor & Francis Group,
2021-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation
by: Huang-Ju Tu, et al.
Published: (2024) -
A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions
by: Tony Eight Lin, et al.
Published: (2018) -
Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
by: Chao-Feng Lin, et al.
Published: (2020) -
In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer
by: Chao-Di Chang, et al.
Published: (2023) -
A Novel Dual HDAC6 and Tubulin Inhibitor, MPT0B451, Displays Anti-tumor Ability in Human Cancer Cells in Vitro and in Vivo
by: Yi-Wen Wu, et al.
Published: (2018)