Preparation of pegylated lumbrokinase and an evaluation of its thrombolytic activity both in vitro and in vivo
Lumbrokinase (LK) is a group of serine proteases with strong fibrinolytic and thrombolytic activities. In clinical practice, LK can only be administered orally because of its antigenicity, immunogenicity and potential to produce anaphylactic reactions after injection. However, many useful drugs such...
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Elsevier,
2013-04-01T00:00:00Z.
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