Mass Spectrometry Reveals Changes in MHC I Antigen Presentation After Lentivector Expression of a Gene Regulation System

• Главные авторы: Roland Vogel (Автор), Reem Al-Daccak (Автор), Oliver Drews (Автор), Jessy Alonzeau (Автор), Gabor Mester (Автор), Dominique Charron (Автор), Stefan Stevanovic (Автор), Jacques Mallet (Автор)
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• Опубликовано: Elsevier, 2013-01-01T00:00:00Z.
• Предметы: article
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The rapamycin-inducible gene regulation system was designed to minimize immune reactions in man and may thus be suited for gene therapy. We assessed whether this system indeed induces no immune responses. The protein components of the regulation system were produced in the human cell lines HEK 293T,...