Delayed Onset of Symptoms and Atovaquone-Proguanil Chemoprophylaxis Breakthrough by Plasmodium malariae in the Absence of Mutation at Codon 268 of pmcytb.

• Egile Nagusiak: Beatrix Huei-Yi Teo (Egilea), Paul Lansdell (Egilea), Valerie Smith (Egilea), Marie Blaze (Egilea), Debbie Nolder (Egilea), Khalid B Beshir (Egilea), Peter L Chiodini (Egilea), Jun Cao (Egilea), Anna Färnert (Egilea), Colin J Sutherland (Egilea)
• Formatua: Liburua
• Argitaratua: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Plasmodium malariae is widely distributed across the tropics, causing symptomatic malaria in humans with a 72-hour fever periodicity, and may present after latency periods lasting up to many decades. Delayed occurrence of symptoms is observed in humans using chemoprophylaxis, or patients having rece...