Delayed Onset of Symptoms and Atovaquone-Proguanil Chemoprophylaxis Breakthrough by Plasmodium malariae in the Absence of Mutation at Codon 268 of pmcytb.

• Glavni autori: Beatrix Huei-Yi Teo (Autor), Paul Lansdell (Autor), Valerie Smith (Autor), Marie Blaze (Autor), Debbie Nolder (Autor), Khalid B Beshir (Autor), Peter L Chiodini (Autor), Jun Cao (Autor), Anna Färnert (Autor), Colin J Sutherland (Autor)
• Format: Knjiga
• Izdano: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Plasmodium malariae is widely distributed across the tropics, causing symptomatic malaria in humans with a 72-hour fever periodicity, and may present after latency periods lasting up to many decades. Delayed occurrence of symptoms is observed in humans using chemoprophylaxis, or patients having rece...