Delayed Onset of Symptoms and Atovaquone-Proguanil Chemoprophylaxis Breakthrough by Plasmodium malariae in the Absence of Mutation at Codon 268 of pmcytb.

• Main Authors: Beatrix Huei-Yi Teo (Author), Paul Lansdell (Author), Valerie Smith (Author), Marie Blaze (Author), Debbie Nolder (Author), Khalid B Beshir (Author), Peter L Chiodini (Author), Jun Cao (Author), Anna Färnert (Author), Colin J Sutherland (Author)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Plasmodium malariae is widely distributed across the tropics, causing symptomatic malaria in humans with a 72-hour fever periodicity, and may present after latency periods lasting up to many decades. Delayed occurrence of symptoms is observed in humans using chemoprophylaxis, or patients having rece...