A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors
Current therapies for glioblastoma multiforme (GBM), the highest grade malignant brain tumor, are mostly ineffective, and better preclinical model systems are needed to increase the successful translation of drug discovery efforts into the clinic. Previous work describes a genetically engineered mou...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2015-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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