Effect of High-Fat Food on the Pharmacokinetic Profile and Safety of SAF-189s, an ALK/ROS1 Inhibitor, in Healthy Chinese Adults

• मुख्य लेखकों: Huiling Qin (लेखक), Yan Tan (लेखक), Lei Diao (लेखक), Ai-Min Hui (लेखक), Zhuli Wu (लेखक), Yongchun Zhou (लेखक), Juan Sun (लेखक), Xiao Xiang (लेखक), Jingjun Qiu (लेखक), Wei Hu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Adis, Springer Healthcare, 2023-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background and Objectives This study was conducted to investigate the effect of high-fat meals on the pharmacokinetics (PK) and safety profile of SAF-189s, a novel ALK/ROS1 inhibitor. Methods This was a single-center, phase I, open-label, crossover study in which healthy adults (≥18 years)...