Effect of High-Fat Food on the Pharmacokinetic Profile and Safety of SAF-189s, an ALK/ROS1 Inhibitor, in Healthy Chinese Adults

Abstract Background and Objectives This study was conducted to investigate the effect of high-fat meals on the pharmacokinetics (PK) and safety profile of SAF-189s, a novel ALK/ROS1 inhibitor. Methods This was a single-center, phase I, open-label, crossover study in which healthy adults (≥18 years)...

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Main Authors: Huiling Qin (Author), Yan Tan (Author), Lei Diao (Author), Ai-Min Hui (Author), Zhuli Wu (Author), Yongchun Zhou (Author), Juan Sun (Author), Xiao Xiang (Author), Jingjun Qiu (Author), Wei Hu (Author)
Formato: Libro
Publicado: Adis, Springer Healthcare, 2023-11-01T00:00:00Z.
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