Effect of High-Fat Food on the Pharmacokinetic Profile and Safety of SAF-189s, an ALK/ROS1 Inhibitor, in Healthy Chinese Adults

• Asıl Yazarlar: Huiling Qin (Yazar), Yan Tan (Yazar), Lei Diao (Yazar), Ai-Min Hui (Yazar), Zhuli Wu (Yazar), Yongchun Zhou (Yazar), Juan Sun (Yazar), Xiao Xiang (Yazar), Jingjun Qiu (Yazar), Wei Hu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Adis, Springer Healthcare, 2023-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background and Objectives This study was conducted to investigate the effect of high-fat meals on the pharmacokinetics (PK) and safety profile of SAF-189s, a novel ALK/ROS1 inhibitor. Methods This was a single-center, phase I, open-label, crossover study in which healthy adults (≥18 years)...