The Chaperone Balance Hypothesis: The Importance of the Extracellular to Intracellular HSP70 Ratio to Inflammation-Driven Type 2 Diabetes, the Effect of Exercise, and the Implications for Clinical Management

The Chaperone Balance Hypothesis: The Importance of the Extracellular to Intracellular HSP70 Ratio to Inflammation-Driven Type 2 Diabetes, the Effect of Exercise, and the Implications for Clinical Management

Recent evidence shows divergence between the concentrations of extracellular 70 kDa heat shock protein [eHSP70] and its intracellular concentrations [iHSP70] in people with type 2 diabetes (T2DM). A vital aspect regarding HSP70 physiology is its versatility to induce antagonistic actions, depending...

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Main Authors: Mauricio Krause (Author), Thiago Gomes Heck (Author), Aline Bittencourt (Author), Sofia Pizzato Scomazzon (Author), Philip Newsholme (Author), Rui Curi (Author), Paulo Ivo Homem de Bittencourt (Author)
Format: Book
Published: Hindawi Limited, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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