Impact of MnTBAP and Baricitinib Treatment on Hutchinson-Gilford Progeria Fibroblasts

Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disease. It is caused by a mutation in the <i>LMNA</i> gene, which results in a 50-amino-acid truncation of prelamin A. The resultant truncated prelamin A (progerin) lacks the cleavage site for the zinc-metallopeptidas...

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Main Authors: Elena Vehns (Author), Rouven Arnold (Author), Karima Djabali (Author)
Format: Book
Published: MDPI AG, 2022-07-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available