Impact of MnTBAP and Baricitinib Treatment on Hutchinson-Gilford Progeria Fibroblasts
Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disease. It is caused by a mutation in the <i>LMNA</i> gene, which results in a 50-amino-acid truncation of prelamin A. The resultant truncated prelamin A (progerin) lacks the cleavage site for the zinc-metallopeptidas...
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MDPI AG,
2022-07-01T00:00:00Z.
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