A Cell Line for Detection of Botulinum Neurotoxin Type B

• Hoofdauteurs: Aleksander Rust (Auteur), Ciara Doran (Auteur), Rosalyn Hart (Auteur), Thomas Binz (Auteur), Paul Stickings (Auteur), Dorothea Sesardic (Auteur), Andrew A. Peden (Auteur), Bazbek Davletov (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2017-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Botulinum neurotoxins (BoNTs) type A and type B are commonly used as biopharmaceutics for neurological diseases, uniquely allowing months-long paralysis of target muscles. Their exquisite neuronal specificity is conferred by a multistep process of binding, internalization, cytosolic escape and cleav...