Endocannabinoid-dependent disinhibition of orexinergic neurons: Electrophysiological evidence in leptin-knockout obese mice

Objectives: In the ob/ob mouse model of obesity, chronic absence of leptin causes a significant increase of orexin (OX) production by hypothalamic neurons and excessive food intake. The altered OX level is linked to a dramatic increase of the inhibitory innervation of OX producing neurons (OX neuron...

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Main Authors: Thorsten Michael Becker (Author), Morgana Favero (Author), Vincenzo Di Marzo (Author), Luigia Cristino (Author), Giuseppe Busetto (Author)
Format: Book
Published: Elsevier, 2017-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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