3H-1,2-Dithiole-3-Thione Protects Lens Epithelial Cells against Fructose-Induced Epithelial-Mesenchymal Transition via Activation of AMPK to Eliminate AKR1B1-Induced Oxidative Stress in Diabetes Mellitus

• Hoofdauteurs: Tsung-Tien Wu (Auteur), Ying-Ying Chen (Auteur), Chiu-Yi Ho (Auteur), Tung-Chen Yeh (Auteur), Gwo-Ching Sun (Auteur), Ching-Jiunn Tseng (Auteur), Pei-Wen Cheng (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2021-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Studies demonstrated that the receptor of advanced glycation end products (RAGE) induced epithelial-mesenchymal transition (EMT) formation in the lens epithelial cells (LECs) of diabetic cataracts. This work investigated how 3H-1,2-dithiole-3-thione (D3T) reduces EMT formation in LECs of the fructos...