3H-1,2-Dithiole-3-Thione Protects Lens Epithelial Cells against Fructose-Induced Epithelial-Mesenchymal Transition via Activation of AMPK to Eliminate AKR1B1-Induced Oxidative Stress in Diabetes Mellitus

• Главные авторы: Tsung-Tien Wu (Автор), Ying-Ying Chen (Автор), Chiu-Yi Ho (Автор), Tung-Chen Yeh (Автор), Gwo-Ching Sun (Автор), Ching-Jiunn Tseng (Автор), Pei-Wen Cheng (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2021-07-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Studies demonstrated that the receptor of advanced glycation end products (RAGE) induced epithelial-mesenchymal transition (EMT) formation in the lens epithelial cells (LECs) of diabetic cataracts. This work investigated how 3H-1,2-dithiole-3-thione (D3T) reduces EMT formation in LECs of the fructos...