Effects of Posaconazole on Tacrolimus Population Pharmacokinetics and Initial Dose in Children With Crohn's Disease Undergoing Hematopoietic Stem Cell Transplantation

• मुख्य लेखकों: Xiao Chen (लेखक), Dongdong Wang (लेखक), Feng Zheng (लेखक), Lin Zhu (लेखक), Yidie Huang (लेखक), Yiqing Zhu (लेखक), Ying Huang (लेखक), Hong Xu (लेखक), Zhiping Li (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The present study explored the effects of posaconazole on tacrolimus population pharmacokinetics (PPK) in children with Crohn's disease (CD) undergoing hematopoietic stem cell transplantation (HSCT). Tacrolimus concentrations, physiological and biochemical factors, and concomitant medications f...