α-1 Antitrypsin Inhibits RANKL-induced Osteoclast Formation and Functions

• Príomhchruthaitheoirí: Mohammad Ahsanul Akbar (Údar), David Nardo (Údar), Mong-Jen Chen (Údar), Ahmed S. Elshikha (Údar), Rubina Ahamed (Údar), Eslam M. Elsayed (Údar), Claire Bigot (Údar), L. Shannon Holliday (Údar), Sihong Song (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: BMC, 2017-03-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Abstract Osteoporosis is a global public health problem affecting more than 200 million people worldwide. We previously showed that treatment with α-1 antitrypsin (AAT), a multifunctional protein with antiinflammatory properties, mitigated bone loss in an ovariectomized mouse model. However, the und...