α-1 Antitrypsin Inhibits RANKL-induced Osteoclast Formation and Functions

• Prif Awduron: Mohammad Ahsanul Akbar (Awdur), David Nardo (Awdur), Mong-Jen Chen (Awdur), Ahmed S. Elshikha (Awdur), Rubina Ahamed (Awdur), Eslam M. Elsayed (Awdur), Claire Bigot (Awdur), L. Shannon Holliday (Awdur), Sihong Song (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2017-03-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Osteoporosis is a global public health problem affecting more than 200 million people worldwide. We previously showed that treatment with α-1 antitrypsin (AAT), a multifunctional protein with antiinflammatory properties, mitigated bone loss in an ovariectomized mouse model. However, the und...