Imperatorin Restores Chemosensitivity of Multidrug-Resistant Cancer Cells by Antagonizing ABCG2-Mediated Drug Transport

• Prif Awduron: Chung-Pu Wu (Awdur), Megumi Murakami (Awdur), Yen-Ching Li (Awdur), Yang-Hui Huang (Awdur), Yu-Tzu Chang (Awdur), Tai-Ho Hung (Awdur), Yu-Shan Wu (Awdur), Suresh V. Ambudkar (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2023-11-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The high expression of the ATP-binding cassette (ABC) drug transporter ABCG2 in cancer cells contributes to the emergence of multidrug resistance (MDR) in individuals afflicted with either solid tumors or blood cancers. MDR poses a major impediment in the realm of clinical cancer chemotherapy. Recen...