INFLUENCE OF C3435T POLYMORPHISM OF THE GENE MDR1 ON THE EFFICACY OF JUVENILE IDIOPATHIC ARTHRITIS THERAPY

Juvenile idiopathic arthritis (JIA) is a multifactorial disease: its pathogenesis includes immunological and genetic factors. Gene MDR1 is responsible for resistance to various cytotoxic drugs. Product of gene MDR1 - P-glycoprotein (P-gp) acts as a transmembrane pump, thus affecting action of drugs....

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Main Authors: F. V. Rokhlina (Author), G. A. Novik (Author), N. M. Kalinina (Author), N. V. Bychkova (Author), Y. N. Filippova (Author), M. I. Zarayskiy (Author)
Format: Book
Published: Union of pediatricians of Russia, 2013-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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