INFLUENCE OF C3435T POLYMORPHISM OF THE GENE MDR1 ON THE EFFICACY OF JUVENILE IDIOPATHIC ARTHRITIS THERAPY
Juvenile idiopathic arthritis (JIA) is a multifactorial disease: its pathogenesis includes immunological and genetic factors. Gene MDR1 is responsible for resistance to various cytotoxic drugs. Product of gene MDR1 - P-glycoprotein (P-gp) acts as a transmembrane pump, thus affecting action of drugs....
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Format: | Book |
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Union of pediatricians of Russia,
2013-09-01T00:00:00Z.
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A1234.567 |
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