Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• Váldodahkkit: Giuseppe Ercolano (Dahkki), Paola De Cicco (Dahkki), Valentina Rubino (Dahkki), Giuseppe Terrazzano (Dahkki), Giuseppina Ruggiero (Dahkki), Roberta Carriero (Dahkki), Paolo Kunderfranco (Dahkki), Angela Ianaro (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...